BIOS and Software
One of the things I've long praised ASUS for is the execution of their UEFI / graphical BIOS. Not only is navigation smooth and seamless, they never forced you to rely on the mouse, and the keyboard navigation worked just as it always did in legacy BIOS. Ontop of that, I think they did the best job creating a functional "simple BIOS" which allowed you to get right to the quick things you might look for out of frequent BIOS entries, like force booting from a particular device without manually altering boot orders or applying a quick automatic tune for more performance or efficiency. And, although it doesn't drastically change my experience (which was already entirely positive), ASUS has further cleaned up the GUI, further streamlined navigation, and added a few neat features like the ability to leave yourself notes from, say, an overclocking session, for future reference. Of course it includes the full range of tweaking options you'd expect from a capable overclocking board and opens up a huge array of micro-tweaking with the Digi+ VRM.
AI Suite 3
This is going to sound like a broken record after reading about the BIOS, but AI Suite 2 has been a crown jewel for ASUS since they've rolled it out. The aim was to not only provide most of the BIOS-level functions on the desktop GUI (which can be more user-friendly and minimize reboot times), but to also cleanly and unobtrusively package all of the nifty features into one clean software package instead of installing a dozen tiny individual software packages which becomes unwieldy and outright annoyinig. AI Suite 2 was great, we've raved about it's ease of use and functionality before. Here's a detailed look we've written about before, and AI Suite 3 continues the same great experience. Access to overclocking features, system monitoring, and custom fan speed profiles, to name a few of the big hitters, still really enhances the overall experience in a big way. Overclocking is much less of a PITA without having to worry about constant reboots, and keeping your rig as quiet as you'd like based upon target temperatures is fantastic. Again, ASUS hasn't tried to fix something that isn't broken, and has instead further refined and streamlined one of their best experiencial features in class-leading fashion.
Wi-Fi GO! & NFC Express
ASUS' Wi-Fi GO! utility also has a large number of features. From using your phone as a remote control for you computer to being able to access your phone's camera, the Wi-Fi GO! utility provides a number of ways to use your mobile device alongside your PC. Setup is super simple, just download the App to your phone, connect to the same network as your PC, and click the appropriate icon in AI Suite III, and you're set! I personally found value in using the Remote Desktop to use my phone as a second "monitor," which is great for stability tests. You no longer need to sit in front of your computer, just use your phone, move your test program to the phone "monitor" and take the screen with you. It's great to be able to do other chores or watch a show in another room and still be able to keep an eye on your computer. You can also use it to control media players, great for changing that song you've been meaning to delete for years but have forgotten.
The NFC Express feature contains two things I find paritcular value in; the first is the ability to quick-tap to login and the other is the ability to setup auto-backup of my phone which I can set right on the box (with a USB cable to charge as well). Technology which creates a passive convenience is my favorite. Otherwise the remote desktop may also be accomplished via Wi-Fi GO! and the quick launch hasn't shown to be a time-saver, so those aspects feel a bit superfluous.